Inoculating B liver vaccine can lower the incidence rate of liver cancer

Since July, 1984, our country Taiwan region carried out B liver vaccine to inoculate a plan.For evaluating the immunity's plan's influence for the liver cell liver cancer formation, professor Zhang Mei Hui etc. carried on as long as 13 years of research."The Taiwanese B liver vaccine inoculates and child the liver cell cancer outbreak lead a relation research" of the announcement suggests as a result on this seminar, B liver vaccine inoculates to obviously lower the incidence rate of liver cell cancer.
Teach introduction according to Zhang Mei Hui, occurrence and hepatitis virus of the liver cell cancer are infected closely related, with B liver virus be infected of the relativity is particularly obvious.In Taiwan, child liver cell cancer and the relativity of B liver virus is stronger than the adult's relativity-child liver cell cancer sufferer serum B liver surface antigen masculine gender rate approach 100%, but adult liver cell cancer sufferer serum B liver surface antigen masculine gender lead to 70%~80%.Therefore, the child the liver cell cancer incidence rate is effectively to respond whether B liver vaccine plan can lower the index sign of liver cell cancer.
In the above-mentioned research, Zhang Mei Hui teaches to wait to the Taiwanese cancer sufferer in the middle of the database July, 1981~July, 1994's 6~14-year-old sufferer's information that contract a liver cell cancer carried on analysis.For ensuring the accuracy of database information, they carried on the children of much center cooperation in the meantime liver cell the cancer registers a research, and recorded sufferer's serum thick HBsAg degree, A foetus egg white(AFP) level and B liver vaccine to inoculate a history, use the outbreak rate of 6~14-year-old child familiar malignant tumor-brain tumor as in the meantime the quality controls to change to measure.
Should study and discover, 1981~1986 period Taiwan 6~14 years old child liver cell cancer on the average the outbreak lead to 0.7 100,000, 1986~1990 the period descend to 0.57100,000, 1990~1994 the period descend to 0.36100,000.The research analysis thinks that 1986~1990 period on the average the outbreak rate descend possibility and vaccine to extensively inoculate planned implementation and make community immunity the dint strengthen relevant;1990~the outbreak rate in 1994's descending further is extensively one of the direct effects that B liver vaccine inoculates.On top of that, the research discovers, child liver cell cancer of ill rate together compare descend:In July, 1990 after, the age contracts liver cell after correcting the cancer dies of illness of the risk be only front for this of 51%.Same period, the outbreak of 6~14 years old child brain tumor's leading don't present to similarly descend trend.Study a period, the total outbreak rate of Taiwanese child's tumor didn't descend as well, but same period the outbreak rate of the crowd over 14 years of age liver cancer present up-trend.(from 11.11 in 1981100,000 rises to 25.82 in 1992100,000)
The liver cell cancer outbreak rate analysis carrying on according to the births set discovers, Taiwan 1974~1984 birth of the 6~9-year-old child about has 15,700,000, be among them diagnosed for the totally having of the liver cell cancer 82;(the outbreak leads to 0.52 100,000)1984~1986 birth of in the 2,300,006~9-year-old child, is diagnosed for the case of liver cell cancer to only have 3.(the outbreak leads to 0.13 100,000)
The conclusion that should study is:Pass to inoculate B liver vaccine, the child of Taiwan the liver cell cancer incidence rate obviously descends.