The cervical cancer ex- pathological changes how should defend 1

3.11.2009

Think currently, the temple neck cancer contains explicit relation with the human milk head-like in shape lump virus(HPV) infection.Can say, the temple neck cancer is an infection disease, can prevent°from, can cure and cure, this because of:①Know it takes place reason;②Earnest census and can prevent°fro with diagnosing;③The diagnosis canned completely cure in early days.Cervix of the pathological changes is an opposite more long-term process before the cancer, this makes intervention and treatment made possible, the key lies in census, early detection and processing.
As for Shai check
The American cancer comprehensive network(NCCN) releases recently of is put forward by 17 norm that authority expert drafts, starting time that the Shai checks is sex to live after the beginning for around 3 yearses, not and late in 21 years old.Terminating time there is 3 timeses above satisfied but normal cytology checks within 10 years after being 70 years old.The Shai checks partition BE, traditional cytology Tu Pian checks annually once;The liquid radicle thin layer cytology checks every 2 years of method(TCT) once.30 years old empress, 3 continuous normal, can 2~3 years is once.The United States FDA grants HPVDNA after examination begin from 30 years old, cytology and HPV examine partition for longer than 3 years not.
In 2003, Chinese cancer research foundation organization expert discuss and release the temple neck cancer Shai to check a guidebook suggestion in 2004, check a start for time in the economic flourishing region Shai for 25~30 years old, the economy owes a flourishing region for 35~40 years old, high Wei crowd all should appropriately advance.Terminate time Be settled to 65 years old.The in the interval separates is onceyear, 2 continuous normal, extension partition go to 3 years;2 continuous HPV-s can prolong partition to 5~8 years.
The Shai checks project and method to as well have a dissimilarity, among them the best project BE:Carry on TCT and HPV examination;General project:Do traditional Ba Shi Tu slice cytology check and HPV examine;Basic project:Mainly is naked eye observation, adopt 3%~5% ice acetic acid dyeing(VIA), 4%~5% iodine liquid dyeing(VILI), and can"namely check namely cure"(See& Treat), although not exert ideal,is also very good measure to the economy not flourishing or poor region.
As for cytology check
The urgent matter of the moment is to promote Bethesda system TBS classification, conditioned unit, promote the calculator assistance temple neck cytology diagnosis technique(CCT) or TCT.
TBS categorizes important point BE:
The scale-like in shape cell pathological changes can generalize for:Not the typical model scale-like in shape cell ASC, include meaning unidentified not the typical model scale-like in shape cell(ASCUS) and not excepted the high pathological changes in the top skin of not the typical model scale-like in shape cell(ASC-H);Scale-like in shape up pathological changes(SIL) inside the skin, including the low degree scale-like in shape last pathological changes(LSIL) inside the skin and high scale-like in shape last pathological changes(HSIL) inside the skin;Scale-like in shape cell cancer(SCC).
As for the new classification of gland cell pathological changes, canceled not explicit meaning not typical model gland the cell(AGUS) is still 4 classes typical model gland not cell(AGC);Incline toward tumor not typical model gland cell(AGC-fn);The neck takes care of a home position cancer(AIS);Gland cancer.
Live check as for vagina mirror the check and temple neck organization
The vagina mirror checks still pathological changes observation and instruction to live to is in the important position in the check at the temple neck, though have fluorescence to examine, the vagina mirror checks still not commutable.Can directly describe the vagina mirror checks a result and may also makes Reid grade point, or Reid the vagina mirror index number RCI evaluation, empress both is to the temple neck pathological changes carry on completely, the objective quantity turns analysis, can raise diagnosis accuracy, also easy to have united valuation of standard.May also to CIN the diagnosis"hang depend".Such as<2 cent, normal;3~4 cents, CINI;3~5 cents, CIN Ⅱ ;6~8 cents, CIN Ⅲ .
The histology diagnosis is the gold standard that the ex- cervical cancer pathological changes diagnoses.(Many)Order to live a check(PB), wreath form, the electricity slices Shu(LEEP) and cold knife awl to slice(CKC) to all have the important histology the diagnosis meaning, but from diagnostic of overall, the accuracy should is a PB to saying.
Concerning diagnose
Above-mentioned cytology, vagina mirror check and histology check since is diagnose a method and as well want one by one in order carry on of three stairs diagnose procedure, generally don't exceed.The cytology is a beginning to start a check, is two other of foundation;Don't blindly live check while having no vagina mirror and checking instruction, unless is very obvious pathological changes;Cytology diagnosis reports according to TBS, the specimen divides satisfied, dissatisfied, canceled original"not enough satisfaction".The diagnostic process drafted plan that we release in 2000 is basic to go, its important point BE:Cytology feminine gender periodical reexamination, Tu Pian dissatisfied need to be reexamined.ASCUS can reexamine after 3~6 months as well as go a vagina mirror check.ASC-H should go a vagina mirror check.LSIL and HSILs should go vagina mirror check, and go organization to live check or neck tube to diagnose to pare off at the mirror bottom, it the result is reported with CIN Class and adopt to correspond a processing.
As for HPV be infected
HPV is mankind cancer lump outbreak in unique can completely confirm of cancer-causing virus.The research in present even can confirm, prevent HPV from being infected and then can prevent°fro temple neck cancer, have no HPV to be infected and then can don't contract a temple neck cancer.
HPV is infected not seldom seen, but the HPV infection only keeping on would take place CIN or temple neck cancer, can take place CINI and CIN Ⅱ and CIN for generally average 8~24 months Ⅲ , can take place again for average 8~12 years gradually a cancer.
The HPV examination contains a lot of methods, at present with miscellaneous hand over to succeed in catching a technique(hC 2) the best, the sensitivity of its examination is 88%~100%, feminine gender predicts that the value is up to 99%, hC 2-can immediately don't have HPV infection by confirmation, and can also report virus burden to follow its growth and decay.
Can be divided into the high Wei to the HPV infectionlow Wei, a lead sex, delay sex and continuously sex is several category types, with Gao Wei Xing be most continuously infected for importance.So HPV examination of the clinical application include Shai to check, excrescent cytology of processing and the temple neck pathological changes treatment empress of with diagnose.For examine HPV as the Shai checks a contents, although still have controversy, a Shai that includes 23890 sufferers of Europe(virtuous, English, method) checks data to suggest, HPV examines an ability to obviously raise Shai to check effect.

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