The cause of disease pathology of urine bladder tumor

The cause of disease urine bladder tumor cause of disease is complicated, real outbreak reason still incompletely clear, according to the result of the clinical observation and the experiment research, probably have something to do with following factor.
(A)Outside source carcinogen:Notice to directly work on the worker of aniline dyestuff in the industrial flourishing nation very early, the urine bladder cancer outbreak leads special Gao, and outbreak rate with work age growth but go up.Empress through clinical observation and experiment the research discover, β -Nai An and allied aniline compound to cancer-causing relevant, found out the metabolism outcome of this material further such as sulfuric acid to accidentally 2-ammonia radicle-one benzene Fen eject in the urine of the density high is normal to be worth 20000%, if don't through the urine bladder wet liquid reposition of redundant personnel to eject, the urine bladder organization then doesn't cancer happen to change.In addition, the carcinogen got in touch with etc. is also thought to is one of the cause of disease that inducts an urine bladder cancer in the smoking, daily life.
(Two)Inside source carcinogen:The color An is sour and cigarette sour metabolism abnormality, among them, the outcome border on the Qian ammonia radicle Fen material, ability synthesizing of RNA and DNA of the direct influence cell, have cancer-causing function, the urine bladder tumor patient wets to increase inside the color An sour metabolism outcome.
(Three)Other cancer-causing factors:After suffering from an Egyptian schistosome disease, easily urine bladder tumor happen because of the incitement of schistosome egg in the urine bladder wall.Our country schistosome disease from Japanese schistosome disease to, don't cause this kind of pathological changes.The urine bladder glues the film white spot disease, gland bladder inflammation, stone calculus, long-term urine to accumulate, some virus infection etc. is also one of the cause of disease that inducts urine bladder tumor.Two, the pathologic urine bladder tumor mostly come from skin cell and have above 95%, but among them above 90% in order to move to go cell cancer, scale-like in shape cell cancer and gland cancer less see, but the malignant degree far and more moves to go the cell cancer as Gao.Not ascend the tumor of skin source such as the horizontal line muscle lump classes and grades is rare.The urine bladder tumor is in changing pathology according to the cell size, appearance, dye a depth, check a change, abruption equal is divided into four classes.A, second class divide better, belong to a low degree ill nature;3, 4 classes divide badly and belong to height malignant.Nipple-like in shape lump cell appearance with move to go cell without the obvious difference as usual, but have already relapsed with bad change to incline to, therefore still see to treat for swollen cancer on the treatment.The urine bladder tumor has a home position cancer, nipple-like in shape cancer in growing a way and gradually sex cancer is 3 kinds, at clinical up three mixtures don't seldom exist to see.Under the urine bladder mirror or live a body specimen great body observation can see a tumor have a Di often is low degree ill nature, wide radicle have no Di is a high ill nature, it is always highly malignant to ulcerate gradually the tumor of type.Clinical up grow depth to gradually expect the method is divided into four period O periods by the Jewett-Marshall cent to the urine bladder tumor:The tumor is limited by to glue a film;The AN expects:The tumor involves in to glue film bottom layer, but don't invade and muscle layer.B1 period:The tumor involves in a shallow muscle layer.B2 periods:The tumor involves in a deep muscle layer, but still invade and the muscle layer Be outside to organize.The C expects:The tumor invades and whole muscle layer and urine bladder surroundings the fat organize.D1 period:The tumor invades and urine bladder the surroundings organize and basin organ inside the chamber, the part has lymphoid knot to transfer.D2 periods:The tumor occurrence distance transfers.The urine bladder tumor at most distributes wall and Houpi at the urine bladder side, secondly is triangle area and coping, its occurrence can be many cooking stoves, may also in the meantime or successively the companion contain the tumor of pelvis, urethra and urethra.Proliferation of the urine bladder tumor mainly is to deep department gradually, after then distance happen to transfer.Transfer path with the Ka lymph knot, the stomach aorta lymph knot is lord, later period minority of patients can transfer to organs, such as lung, bone and liver...etc. from blood.The urine bladder cancer transfers occurrence a little bit late and spread a little bit slowly.