The course of illness of the chronic grain cell leukemia cent expects

Chronic grain cell leukemia at clinical up develop process to is divided into according to the paroxysm chronic period, the acceleration expect with nasty change to expect, this to clinical treatments with prepare after germane.

Chronic grain cell leukemia the chronic expect to have no symptom or have low heat, tired and much sweat and weight to ease etc. symptom, the outside week blood white cell counts to increase Gao, mainly for take care of the young in the neuter gender grain, late take care of the young grain and pole-like in shape pit grain cell, love sour and love an alkali grain the cell increase, can have jot have already checked red cell, the marrow elephant increases to living obviously active to extremely active, with grain the cell system increase to living for lord, neuter gender medium young grain, late take care of the young grain and pole-like in shape pit grain cell increase, the original cell comparison ≤ is 10%.The cell genetics check discovers the Ph chromosome with an abnormality.

About 70% patients in chronic grain cell leukemia the diagnosis establishes after 1~4 year, , average 40 in month, can be languid, tired, night sweat, the weight eases, can appear not clear reason of have fever, anemic, the bleed, skeleton ache and spleen carry on sex swollen big, the outside week blood hemoglobin carries on sex to descend, the blood platelets counts to carry on sex to lower or increases Gao and love the alkaline grain cell increases, outside week blood and the original cell comparison in the marrow more chronic expect to have increment, the check detection of the cell genetics has Ph chromosome outside of other excrescent chromosomes appears, patient's medicine in once using formely cures invalid.This stage is called an acceleration period, can keep on for few months, even 1~2 years.

After expecting after acceleration the patient turns to go into nasty change to expect, minority of patients after diagnosing few months namely take place nasty change, the patient, who also accidentally have, will just change to acceleration to expect in more than ten years.Chronic grain cell leukemia the chronic canned be attained to alleviate by medicine treatment but have no symptom while expecting, but nasty after becoming, a little bit original treatments contain no longer valid method, if various symptom has fever, anemic, bleed etc. not easy control, blood elephant and marrow elephant the variety is close the performance of impatient leukemia gradually.