The treatment of unprogressive sex cancer pain

3.10.2009

For long time, the academic circles has been existing a kind of issue, the focus of issue BE, the cancer pain is actually a kind of symptom or a kind of disease.Think currently, can is divided into two types of of cancer pains, 1 type is pain for general cancer or says the symptom cancer pain, this kind of cancer pain adoption general of the norm medicine treatment can immediately alleviate, and carry on a nervous system electricity to the sufferer the physiology or image learn a check to discover the machine quality damage.At this stage, the cancer pain isn't a disease, just a kind of symptom, as long as cure a project to the medicine according to WHO three stairs medicines, can acquire better curative effect.But if this kind of symptom cancer pain doesn't in time cure, will convert into unprogressive sex cancer pain, then adoption the normal regulations medicine cure the ache still don't easily alleviate, and the companion contains the cancer pain of nervous system damage.
A bit painful cancers so hard cure, think currently is because sufferer's nervous system is subjected to damage, for example the tumor oppress nerve, tumor gradually the nerve, blood vessel and bowel take care of, the tumor bone transfers, the cancer gradually arrives chest film, peritoneum or periosteum, surgical operation with put to treat harm nerve, tumor to cause a digest way Geng Zu etc., if the treatment don't will convert into unprogressive sex cancer in time pain.
The classification of unprogressive sex cancer pain
The mental derangement rational cancer painful mental derangement rational cancer pain means the ache that axis or the outside week nervous system that the tumor progress causes hurt comprehensive advertise for, ache over a long period of time existence will cause the nervous system function occurrence change.Its main characteristic is:Self-moving sex ache, the pain feels allergic and the pain feel super quick.Think currently, the mental derangement rational cancer pain is to exist with cancer in the meantime of a kind of chronic ache disease, be clearly incompletely still taken bad a mechanism, but can affirm to have something to do with nervous system hurting, clinical up cure more difficult, is that one in the painful chronic cancer research is a little bit hot.Anesthetic in the bureau alleviates a rate to the mental derangement reasonableness pain although Gao, need to be continuous to the medicine, another neurosurgery surgical operation also has certain effect.
Nerve's oppressing sex painful nerve oppression pain is a Zhui bone to transfer the result that the sexually transmitted disease changesh, in early days changed is what function, can go against, ache of symptom and body advertised for to press the nerve skin distinction cloth, to slice medicine than the mental derangement rational pain more sensitive, sugar skin quality hormone can make the dropsy of oppressing the part and burning the disease can alleviate and lent support to an analgesic.
Sympathetic nerves continuously sex painful sympathetic nerves keep on sex the pain is a sympathetic nerves to hurt an empress of linger effect-like in shape, the basic characteristics is to burn bright kind ache, feel an obstacle, adopt the diagnosis sympathetic nerves Zu Zhi behind alleviate such as the ache, felling the obstacle converse, can confirm.
Burn sex neuralgia and CRPS recently, CRPS(the compound partial ache comprehensive advertise for) this phrase is used to describe usually sympathetic nerves keep on sex ache and bright sex neuralgia, main performance is very violent ache, the companion has dropsy and perspire abnormality, skin temperature variety etc. sympathetic nerves symptom;The skin becomes thin, the bone atrophy etc. the partial malnutrition body advertise for, joint stiff etc. function obstacle;Excrescent ache, felling allergy and feel to lower etc. a consciousness abnormality.
Current research confirms that keeping on the existent ache can make the ache aggravated, its reason is a continuously streaming into of the ache signal to make the nervous system taken place function and pathologic sex damage, therefore think, the violent ache can turn into into unprogressive sex cancer over a long period of time pain, but become a kind of disease, this stage ache cures very difficult.Therefore promote, be ache still a kind of symptom should actively cure.
Be taken bad a mechanism
The mental derangement rational ache is a kind of disease of nervous system, is sensitized by the axis and the outside week sensitize the causable, is the main reason of unprogressive sex cancer pain.
Among them, the outside week sensitizes of occurrence mechanism BE, various nerve harm that the reason results in causes a different impulse, the latter causes nerve harm part and carry on the back a nerve stanza cell membrane Na+the passage density increase Gao, among them the globefish poisonous sensitive Na+the passage can lie to lead nerve impulse in the conduction on the nerve fiber, these self-moving different the impulse constantly stream into spinal cord, can cause and maintain axis to sensitize.In addition sympathetic nerves and immune system all have a certain function.
Woolf etc. passes an animal experiment confirmation in 1983, organization, nerve hurt or severely stimulate an entry-level to stream into the C fiber can cause spinal cord carry Cape nerve on spinal cord's back the dollar excitement continuously goes up, this phenomenon is called that it sensitizes for axis.The entry-level streams into the Tu of that fiber and spinal cord carry Cape nerve dollar on fiber and spinal cord's back to touch to deliver the plasticity variety is the main reason that the axis sensitizes.This kind of plasticity means, if the ache keeps on existence, ache's taking place a mechanism will also keep on;If the ache keeps on disappearance, the ache mechanism can also alleviate or disappear, this provideds a basis for treatment.For example give ache sufferer the norm medicine,such as American Shi Kang, certainly cure, the ache disappears over a long period of time, and the originally formative plasticity variety may also weaken and recover and express to have to lower for the medicine amount of, but the ache still can control.
The treatment of unprogressive sex cancer pain
The medicine treatment is foundation, the head chooses morphine+NSAIDs, increase on this foundation three wreath anti-s suppress a Yu medicine+the anti- surprised Jue medicine;(card Ma Xi Ping, add Ba Pen Ding )The plasticity change that aims at to carry on the back a nerve stanza, can the considering give inside the Zhui tube medicine, such as morphine consociation cloth compare card because of+cola settle;Minority of serious sufferers can accept the derogation nerve Zu Zhi treatment.
For explosion ache, can adopt the subcutaneous injection chlorine An Tong to add to take orally morphine or subcutaneous injection morphine.For the nerve oppression pain, can unite application morphine and skin quality steroid, such as American Shi Kang settle associately take orally to sprinkle Ni loose can alleviate the nerve oppression pain.
Majority of sufferers with painful cancers are cured by three stairs of norm, the ache alleviates a rate exaltation.Minority of cancers painful sufferer's curative effect is dissatisfied, should consider other methods.For example the radio frequency nerve damages Shu to used for the cancer painful treatment to acquire good effect and provideds a new choice for minority of sufferers with painful unprogressive sex cancers in recent years.
In fine, the medicine treatment of unprogressive sex cancer pain should mainly apply the slice medicine is led by morphine to choose, on the other hand that medicine town pain effective, another sufferer is applied behind the emotion also has an amendment.Various slice the medicine all is carried out by body through an excited μ town pain, still didn't be a kind of currently painful effect in the town of slice medicine exceed morphine.

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