The goiter lump divides degree and biology characteristic to is divided into according to it positive with malignant two major types, positive many is gland lump, malignant much is gland cancer.
(A)thyroid gland gland lump(Thyroidadenomas)
Can be taken place to any age, the female much sees, generally have an integrity of wrap a film, each on the size and the histology characteristic don't can is divided into 3 same alike:Nipple form, filter bubble and Hiirthle cell.Filter to steep the sex gland lump at most sees, according to filtering the size of bubble and canning is divided into huge filter bubble(or the gum quality), baby(or small filter a bubble) and embryo, there is also non- typical model of gland lump, this turning of lump returns ① slowness growth;②The occurrence backs to go sex to change;③Take place bad change.Filter a bubble sex gland lump the organization divide degree better, approach normal gland organization, the thyroid gland function measurement the great majority are normal, but its function is opposite independence, be free from TSH to regulate or is seldom regulated by it.Often the performance knots stanza for the single in the gland, diameter for a few millimeters go to a 10 cras above don't wait.General growth slow-moving, much have no oppress symptom.About 90% positive gland lump not the ability Be thick to gather TcO~-or radio iodine, the thyroid gland flicker scans to lose for function or presents "cold knot stanza", the easy misdiagnosis is a cancer.Clinical top in addition to touching a neck lump have no special performance, minority of gland lumps has thick gather iodine of function, scan to show "Wen Jie Jie", the serum thyroid gland hormone TSH the level is normal, changes at any time, the function independence of the gland lump increases Gao and synthesize and secrete the thyroid gland hormone increases and hang a body to secrete TSH is repressed, knot the gland organization outside the stanza atrophies and knots the stanza area radio"' the I is thick to gather to show for" heat to knot stanza", clinical performance is A Kang, call high function gland lump.When the gland lump is more big, can take place issue of blood, back to go sex to change, bad dead or bag change, scanning can present "cold knot stanza", and the function loses, but the gland organization outside the lump can recover function at this time.The high function gland the lump very few cancer changes, curing can the surgical operation takes off in addition to, radio"'I and anti- thyroid gland medicine cure.
The one who have to love acidity grain in the gland cell in the gland lump, be called Htirthle cell gland lump.The nipple-like in shape gland lump less sees, present bag more and be called nipple-like in shape bag gland lump.
The thyroid gland benign tumor that other lesses see has the Ji foetus the lump, afferent lump and smooth muscle lump etc..
(Two)thyroid gland gland cancer(thyroid carcinoma)
Canning be taken place to any age is seen to elder more, the list knots stanza far compare knot the stanza thyroid gland cancer more to see bubble cell more a cancer and filter a bubble side the cell cancer, the thyroid gland lymphoid lump and tumor are even seldom seen.Familiarly have already filtered to steep a cell cancer and filter a bubble side the cell cancer, the thyroid gland lymphoid lump and tumor are even seldom seen 1.Filter bubble cell cancer according to organization the appearance learn and it can is divided into a nipple form and filter bubble form and have never divided a cancer after preparing 3 kind.
(1)nipple-like in shape cancer(papillary carcinoma):Clinical the most familiar, the malignant degree is the also the lightest and share 50%~70% of thyroid gland cancer, Be seen to the child and the youth female sufferer more.(40 before the year olds)Men and women of compare to 1:2~3.The nipple-like in shape gland cancer grows in all thyroid gland cancers the most slow-moving, can limit in the thyroid gland for few years, can spread to the gland body other parts or the partial lymph knots from lymphoid tube inside the gland.Enlarge with the age, the malignant degree can increase Gao, accidentally can convert into don't divide a cancer, differ very much after preparing.On the pathology it is thus clear that divide good and pillar-like in shape up the skin presents nipple-like in shape Tu to rise and check the clear companion loves acidity afterbirth syrup, often it is thus clear that the calcium salt of the united at heart circle deposition.Clinical top in addition to Men and thyroid gland knot stanza and part lymph knot swollen express rarely greatly, scan to present cold knot stanza, the neck X line slice can show to have calm and steady thin point-like in shape or united at heart circle-like in shape calcium salt inside the gland body.The nipple-like in shape gland cancer can be stimulated by TSH but grow, using the thyroid gland hormone can make it narrow.If the surgical operation wraps a film integrity but have no assignor, the life limit is normal.After some years appear to relapse a cancer to the side gland body after suffering from the side thyroid gland cancer resection sometimes.
(2)filter a bubble-like in shape cancer(follicularcarcinoma):Share 10%~15% of thyroid gland cancer around.Much Be seen to 40 years old the female sufferer is with the Wu.Its malignant degree is higher than a nipple-like in shape cancer and hardly transfer from the lymph, filtering a bubble form the cancer can mix up with nipple-like in shape cancer but become mixture type a gland cancer.On the histology it is thus clear that the gland body contains size don't wait of filtering and steeping the cancer cell presents gland tube-like in shape arrange, it is thus clear that nuclear fission, also it is thus clear that have already loved acidity to change.Accidentally it is thus clear that have the sand grain the small body.Clinical up mainly express in order to knot stanza goitre, the list knots stanza to much see, the quality is hard like stone, more fixed.Sometimes can involve in the whole thyroid gland, or can erode close by organization but to ache or have already oppressed symptom.Easily transfer to distance through a blood line, transfer to stand first by lung department, the time is a dirty machines, such as skeleton and liver...etc..Filter a bubble form cancer and its transfering cooking stove have already shot iodine of function, accidentally can the bow I rise A Kang.
(3)do not divide a cancer(anaplastic carcinoma):Its malignant degree is very high.Share 5%~10% of thyroid gland cancer.Be seen to sufferer over 50 years of age more, the female is slightly more than a male.In order to become the dividing of slice bad last skin cell performance of histology, familiar have nuclear fission mutually.Can is divided into a shuttle type according to the appearance of cell cell, big and small afterbirth and cellule type the cancer is 3 kinds and may also take cellule and big and small afterbirth cancer as the most important for several mixtures of category type.The cancer is swollen to make much way and quickly enlarge in the short run, can quickly gradually adjacent organization and extensively transfer all over, like skin, blood vessel, and oesophagus...etc., can cause voice hoarse, spirit way not Chang with swallow difficulty etc. symptom.The lump is big but has already pressed a pain and organize with surroundings mutually and fixedly, movable degree bad, the quality is hard like stone, part the lymph knot much swollen big.The cancer is swollen in early days or before having never discovered original hair cooking stove, can have whole body the distance transfered, like organs such as oesophagus, skin, blood vessel, skeleton and lung etc..Have never divided a cancer to have no thick gather the function of iodine, scan to present "cold knot stanza".
2.Filter a bubble the cell cancer(para-follicular cell carcinoma (MedullarycarcinomaVery easily erode lymph inside the thyroid gland tube, spread to other parts and part of gland body lymphoid knot;Canning also go to spread to distance through the blood is like lung, skeleton and liver.The Sui kind cancer generally didn't wrap a film, the cell appearance that pathology sees and arrange different.Cell can in order to don't divide there is nuclear fission, but have no bad dead or check cell more gradually.Clinical up generally and first have the thyroid gland the strong and tough knot stanza or the part lymph knot swollen big.Sometimes can also first discover that the distance transfers cooking stove and knots stanza not to shoot iodine and scans to present "cold knot stanza", sometimes can express be red for serious diarrhea, stomachache and face tide.Its reason possibility has something to do with the bowel afferent and live Mao that the cancer organization secretes and serum vegetable.The cancer is in great quantities swollen to often secrete to decline calcium of vegetable, but the blood calcium isn't generally low.This disease can the companion has already loved chrome cell lump and A-like in shape side gland gland lump and glue film nerve lump.This namely delivers sex endocrine gland lump Ⅱ more, Ⅲ type..
3.The thyroid gland lymphoid lump(1 ymphoma.The pathologic abnormal shape and lymphoid cell inside the quality presents to fill the air sex gradually and pour filter a bubble to living hair center to atrophy disappearance, the lymphoid cell becomes a heap or wreath-like in shape gradually, the thyroid gland filters to steep the last skin breakage, the afferent wall particularly contains a muscle layer the small afferent wall have lymphoid cell gradually, clinical top chronic and lymphoid cell the thyroid gland is burning or the A Kang sufferer have the goiter piece of quick aggrandizement and scan to present "cold knot stanza", the immunity globulin marking wants to consider this disease for the light chain single gram of Long.This disease;Easy confuse with the cellule type that hasn't divided a cancer, need mirror check the pathology discriminate.
The doctor classification of goiter lump and clinical performance
3.13.2009
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