The cause of disease of temple neck cancer

Up to the present, the cause of disease of temple neck cancer still without the hard conclusion.Majority of authors think to is the result of various factor functions, its outbreak with early marry, early teach, the fecundity, temple neck is repeatedly debauched and once had sexual intercourse, smegma and sex hormone maladjustment etc. factor are relevant.Also have relation with social economic condition and spirit stimulate.Not a few authors put forward a virus cause of disease recently theory.
A, early marry and early teach to produce with Yun repeatedly many
Occurrence and sex of the cervical cancer is living germane, the great majority temple neck cancer sufferer is married women, the single sufferer rarely sees.Lead early sex life or early marry women cervical cancer outbreak the rate show Zhao to increase Gao.The prevention and cure cooperation set of temple neck cancer in Peking City reports 20 years old got married before of fall ill the rate was higher than 21~25 years old set 300%, compare 26 years old hereafter get married Gao 700%.In the meantime the incidence rate of temple neck cancer with produce increment but pass to increase, more than 7 foetuses are taller than the women of 1~2 foetuses 1000% above.Report the one who grow more than 5 foetuses in Anhui, temple neck the cancer fall ill lead compare 5 foetus the following of Gao 500%.
Two, the temple neck is debauched and split wound and outside turn over
Because the physiology of the cervix and dissect up of cause, easily suffer factor incitements such as various physics, chemistry and living creature etc., including wound, hormone and virus etc..The occurrence cervix debauched existence of the temple neck cancer contains close relation and gets the temple neck debauched, the outbreak of temple neck cancer leads higher.Wait analysis and have the temple neck the debauched women according to Lin Qiao Zhi, the temple neck cancer incidence rate is 0.73% and show Zhao is higher than to have no 0.10% of temple neck debauched women.Census detection in Peking City(1972~1976) has the outbreak rate ratio of debauched set to have no debauched set Gao 200%.The temple neck splits to harm and cancer of the occurrence also has a certain relation.
Three, smegma factor
Some clinical data point out that the person's smegma not only has decisive influence to the occurrence of the penis cancer, but also is as germane as the occurrence of the cervical cancer.Epidemiology research proves that the Jew almost could not see the occurrence of penis cancer, the Judean women's cervical cancer incidence rate is also very low in the meantime.Other such as the temple neck cancer incidence rate in the Muslem women is as well lower.Its reason and Jew and Muslem religious rules boy the routine outer skin wreath slice of the customs is relevant.Hint the smegma may be a taking of virus or chemistry carcinogen.Foreign someone once inducted a small rat cervical cancer to achieve success with mankind's smegma.Local Wang Heng Wen waits to confirm a person prototype smegma or the smegma total fat to all have a cancer-causing function to the skin of the small rat cervix and the vagina.Think currently that the cholesterol in the smegma can change into carcinogen after germ function.
Four, virus factor
Recently already affirmative some viruses can induct animal tumor, continuously someone confirm a cervical cancer relationship with the virus of pimple rash.In the cervical cancer cell, see virus grain, shed off cell with the temple neck that the immunity fluorescence antibody method discovers a temple neck cancer patient in, imply the Ⅱ type of pimple rash virus.
In addition, the serology research discovers, in the sufferer of cervical cancer, the antibody masculine gender rate of the Ⅱ type virus of pimple rash is up to 80% or so, but normal women's masculine gender lead only 30% or so.Nobmias waits the pimple rash in the census general crowd of virus Ⅱ the infection of the type lead to 0.10~0.15%, but temple neck before the cancer and cancer the sufferer win to then obviously increase.The following of virus infection sufferer who passes to grow a way to have the Ⅱ type the pimple rash to the female, discover the incidence rate of temple neck cancer to compare with matched control, Gao 600%.
In recent years, a little bit domestic and international researches express, the human milk head lump virus(humanpapillomaVirus call HPV) has something to do with the occurrence of the temple neck cancer.For example tumor graduate school in the Chinese medical science science, hospital etc., to the HPV16 type in the temple neck cancer organization DNA the related sequence carry on an examination research;River the west medical college adoption PAP the immunity Mao dyes a method and carries on HPV to each kind of temple neck organization the examination of the particularity antigen, all hint that the outbreak of temple neck cancer has relation with HPV infection.
Five, sex hormone factor
The estrogen can promote on skin of growth and incitement temple neck of womb and vagina organization increase to living.Someone alone makes the small rat inducted a cervical cancer with sour female plain two Chunseseses of benzene As.There is as well an animal experimenting a proof, estrogen to the A radicle Dan Mao wait carcinogen to induct a small rat cervical cancer have already promoted a function.Remaining Ming Peng discovers that the home position cancer early expects a temple neck a cancer while studying the hormone metabolism of temple neck cancer sufferer patient, wet is as higher as female comparison of three Chuns inside the female two Chunses and female Tong.The gestation expects estrogen level inside the body a little bit not Yun period Gao 25~4000%, can make skin of pregnant woman cervix show Zhao to increase to living, even take place similar not the typical model increase to living or the change of home position cancer, but the postnatal period can recover gradually as usual.
In a word, the real cause of disease of temple neck cancer is still not clear.Think currently, the comprehensive function of various factor, as to it's be taken bad important meaning.