Smoke with lung cancer

1 Meta of main dangerous factor concerning Chinese crowd lung cancer occurrence analyzes enunciation:The main factor that influences Chinese crowd lung cancer occurrence currently is a spirit factor, smoke cigarette, indoor environment pollution, breathe system disease and household history, vegetable and fruit to absorb quantity etc..
There has been inside the global scope since 50's in last century a great deal of Epidemiology research confirmation the smoking is to cause lung cancer of initial dangerous factor, the lung cancer death has 87% is because of what smoking causes, the smoking can produce 40 various carcinogens in the process and relate to with lung cancer to closely mainly have many wreath Fang hydrocarbon compound, benzene, arsenic, C Xi, nicotine(nicotine), carbon monoxide and smoke tar etc. among them, these carcinogens can pass a different mechanism and cause the damage of skin cell DNA of bronchus, activating of some cancer genes, suppress mutating of cancer gene and lose to live, cause cell heredity information conversion the cancer change.
Smoke cigarette relationship with the lung cancer dangerous degree and the category, beginning of tobacco smoke cigarette of age, smoke cigarette of time limit, smoke cigarette quantity relevant, in the different tobacco category with the long term absorb cigarette most is dangerous, the opposite and dangerous degree can reach to 9.0, only take out cigar or the pipe dangerous degree lower, absorb not to take filter mouth smoke or many tars the dangerous degree of the lung cancer is higher than filter mouth or low tar.American cancer association expresses to the brigade row research of 25 states, starts smoking cigarette age is younger than 15 years old, 15-19 years old, 20-24 years old and 25 years old above, the opposite and dangerous degree of its lung cancer one by one in order is 15.10, 12.81, 9.72, 3.21.The of smoke cigarette and lung cancer exists an obvious quantity the effect relate to, the lung cancer brigade row research result enunciation of Doll to British doctor, smoke cigarette 5-14 and 15-24, 25-49ses every day, the opposite and dangerous degree of its lung cancer distinguish are 7.5, 9.5 and 16.6.While smoking cigarette quantity under the fixed circumstance, smoking cigarette time limit to distinguish for 15 years, 30 years and 45 years, the lung cancer exceeds the ratio of outbreak rate is about 1:20:100.Study enunciation smoking and different lung cancer cell the types all have the amount of-effect the relation, but in contacting strength, smoke cigarette is more obviously high than a gland cancer with the relation between scale cancer and cellule cancer, and smoke cigarette the influence of the time limit upon the cell type more more important than the amount of smoking in everyday, the smoking time limit has the amount of-effect the relation to all cell types, but with the relation of scale cancer than to the gland cancer is clearer and distinct.Tumor graduate school in Shanghai research result enunciation, the crowd of different cell type returns because of dangerous degree(PAR%), male scaleoats of PAR is 85%, gland cancer is 33%, the female explains that the regardless male or female smoking causes a scale for 48%, 6% respectivelyoats cancer of PAR%BE bigger than a gland cancer.
A great deal of of Epidemiology research result enunciation, quiting smoking can cause lung cancer outbreak rate of descend, this also explained the danger increment that smoking makes the lung cancer taken place from the reverse side.England since 1950 the smoking of whole country, quit smoking to check against a research to carry on a comparison as a result with the popular trend of lung cancer and two big sample cases with 1950 and in 1990.Conclusion:The smoker evens if arrives middle age to quit smoking,will reduces hereafter danger of suffering from the lung cancer.The middle age quitted smoking the danger that can reduce above 90% to return because of tobacco before.If the smoker in nowadays gives up a smoking habit, in the near future and the first half period death rate in 21th century will keep on to descend.But young man hereafter become to keep on smoker, will consumedly influence its death rate in 21th century middle or second half period.In order to limiting the law of the smoking and the implementation of the regulation, at some western countries in England, the United States and Holland etc., the nearer in the last years' male lung cancer death rate has already been placed in a stability or descends appearance, England male 1950 of lung cancer death rate is 38.28100,000, increase to 75.24 in 1974100,000, hereafter present to descend trend.Male death rate in the United States is 18.13 in 1950100,000, reach to 58.16 in 1990100,000, year by year descend behind from 1990, 2000 is 46.89100,000.The lung cancer age curve appears above 65 more year olds age set have different degree of increase Gao, 45 years old-60-year-old stability or motion, the 40-year-old set slightly has been already descended and indicate from now on these national lung cancer death rate will present to descend trend.
Smoke cigarette and the being in conjunction with of other dangerous factorses of the lung cancer the function is also valued day by day, a concerning lung cancer sufferer p 53, K-ras the gene mutates of Meta analysis enunciation, smoker this two gene mutation the rate is aller high than non- smoker, p 53 genes total ORs is 2.588(95% CIs is 2.358-2.842), the K-ras gene mutates total OR to 4.597.(95% CIs is 3.764-5.615)
The whole country smokes cigarette in 1996 behavioral of Epidemiology survey suggest as a result, national crowd always the smoking lead to 37.6%, the smoking leads to 35.1% and often absorbs to lead to 34.1% now and start smoking cigarette age a little bit in 1984 advance 3 years old.The male smoking leads to 66.9%, the smoking leads to 63.0% now, often the smoking lead up to 61.4% and rose a little bit in 19845%, start smoking cigarette of age a little bit in 19842.7 years in advance.The female smoking leads to 4.2%, the smoking leads to 3.8% and often absorbs to lead to 3.4% and starts smoking cigarette age to compare a male night for 5 years now, and the age don't smoke cigarette a rate have been presenting up-trend.The pollution and breakage that turns to industrialize turning worse of progress and mankind's living environment with town along with the population advanced age especially smokes cigarette continuously increasing of the population, at the coming 20 year, , our country outbreak and death rate of the lung cancer will also continue to increase.
Smoking not only endangers smoker I health, also will because of the tobacco smoke(ETS) that the passive non- smoker inhale a great deal of environment endanger it health.ETS is mainly flowed smoke and essential smoke by side to constitute, the side flows a smoke to compare the cancer-causing compound that the essential smoke contains higher level, like benzene, formaldehyde, Pian and N-second nitric An, and aniline...etc..According to the report way, absorb a smoke, the strong carcinogen N in the essential smoke-the second nitric An is a 4.1-31.1 mgs, while the side flow smoke but is 597-735 mgs.A prospect in Japan brigade row studies result enunciation, weighing a degree the not smoking cigarette of the smoker risk that wife suffers from lung cancer is higher, and the existence measure-effect relation.Blot will many relevant passive smoke cigarette to relate to with lung cancer of research comprehensive discussion, point out that the wife of non- smoker suffers from the risk of lung cancer to increase 30%(RR=1.30) because the husband smokes cigarette, husband heavy degree the RR for smoking cigarette be worth up to 1.70.Our country when Gao Yu Tang waits research female lung cancer cause of disease in Shanghai think that the wife doesn't smoke cigarette but husband's smoking, because the passive smoking causes the RR of lung cancer to live together the increment of the time limit in time with the husband but ascension, live together for more than 40 years RR=1.7, the scale is as higher as the RR of cellule lung cancer.